A new study reveals a previously unknown deficit in high-intensity exercise

New York, Nov 19, (Agencies): In a disturbing revelation for over-exercising fitness enthusiasts, a recent study that analyzed more than 4,700 molecules in firefighter’s urine exercising the peritoneal cavity demonstrates the negative effects of excessively intense exercise on the immune system be | . . . . . . . . . . . . . . . . This finding may have implications for individuals with physically demanding occupations, such as emergency personnel and athletes.

According to Ernesto Nakayasu, a biological scientist at the Pacific Northwest National Laboratory (PNNL), extremely healthy individuals may develop respiratory infections immediately after strenuous exercise Nakayasu suggests that the reduction in inflammatory activity required to prevent infection could be a contributing factor .

While it is widely accepted that moderate exercise has long-lasting benefits for the immune system, the immediate effects of high-intensity exercise are within the body effect on the immune system remains a matter of debate and existing evidence that strenuous physical activity may increase the risk of opportunistic infections is the size is invisible. Previous studies have reported self-reported upper respiratory tract infections in athletes after strenuous activities, but it remains uncertain whether these findings suggest that with is connected or caused

To dive deeper into the physiological changes induced by strenuous exercise, Nakaya and colleagues analyzed comprehensive blood, urine and saliva samples from 11 firefighters beforehand 45 minutes of vigorous exercise on weights requiring approximately 20 kg (44 lb) of lifting and a stable background.

PNNL bioanalytical chemist Kristin Barnum-Johnson explains the motivation behind the study, emphasizing the importance of understanding the early signs of danger from fatigue. The researchers hope such insights can help reduce the risks of strenuous exercise for first responders, athletes and military personnel.

While exercise undoubtedly provides many health benefits, the study revealed potential signs of immune compromise in firefighters undergoing strenuous exercise What sleep notably, a decrease in inflammation-related particles accompanied an increase in opiorphin, a substance that dilates peripheral blood vessels

The implications of these changes in short-term immune function remain unclear, but researchers hypothesize that opiorphin may increase arterial blood flow during exercise. mu-scle, to improve oxygen and nutrient delivery. It is suggested that the mechanism

Changes were also noted in the participants’ oral microbiome, possibly due to increased levels of antimicrobial peptides in the firefighters’ mouths after activity but with the effect of these peptides in protecting against infection host response, especially inhibition of E. coli growth, is limited

While some argue that the observed changes may reflect a higher level of immune surveillance and control rather than immune suppression, the study’s small sample size and specific pollutants exposed during fires require further investigation Chap.